The hypereosinophilic syndrome in acute lymphocytic leukemia

Hypereosinophilic syndrome terminating in acute myelogenous leukemia.

The role of microRNA in acute/chronic, myeloid/lymphocytic leukemia

MicroRNAs are small, non-coding sequences that regulate gene expression by inducing degradation or translational inhibition of target mRNAs. These molecules control many intracellular physiological and pathological processes.Abnormal expression of these moleculs has been described in different cancers including hematopoietic cancers. According to the type of cancer and the stage, miRNA’s expres...

Hypereosinophilic Syndrome Simulating an Acute Coronary Syndrome

Objectives: To report a case of hypereosinophilic syndrome which presented clinically as acute coronary syndrome. Materials and methods: We describe the case of a 69-year-old woman with acute coronary syndrome and peripheral hypereosinophilia. Results: The condition rapidly evolved to severe heart failure. Coronary disease was excluded by cardiac catheterization. Systemic corticosteroid therapy...

Hypereosinophilic syndrome causing acute hemiplegia in childhood.

Hypereosinophilic syndrome (HES) is a rare heterogeneous group of disorders, characterized by marked peripheral blood and tissue eosinophilia resulting in end organ damage. This case describes a six-year-old girl child who presented with sudden weakness of right half of body and fever. Computed tomogram of brain showed infarction of left internal capsule and basal ganglia. She had peripheral an...

Acute Lymphocytic Leukemia

By Alvin M. Mauer I T IS TRULY gratifying to review the progress that has been made in the therapy of the acute leukemias since the introduction of aminopterin by Farber and coworkers’ in the late I 940s. This progress can be measured by the increasing proportion of patients who have achieved complete remission, the increasing duration of their survival, and the increasing evidence that for som...